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Spermidine improves the hallmarks of aging by causing autophagy, the function of cellular regeneration. It works as a caloric regulation mimetic (CRM) that simulates fasting results in the body. Spermidine is of interest to scientists in the context of aging because it is a key morphogenetic determinant for the lifespan of cells and living tissues.

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Description

Essential Roles in the Body:

  • Cellular Function: Spermidine plays a crucial role in various cellular processes, including protein synthesis, ribosome biogenesis, and cell differentiation.
  • Autophagy Induction: It triggers autophagy, a cellular housekeeping process that recycles damaged parts and promotes cellular health.
  • Stress Resistance: Spermidine helps cells resist stress factors like oxidative stress and inflammation, potentially delaying aging.
  • DNA Repair: Its role in autophagy may indirectly support DNA repair and protect against cellular damage.

Impact on Longevity:

  • Preclinical Studies: Studies in various animal models, including worms, rodents, and even honey bees, have shown that spermidine supplementation extends lifespan. While directly translating these findings to humans requires further investigation, it paints a promising picture. Check one study by pressing here.
  • Reduced Mortality Risk: Observational studies suggest a link between higher spermidine intake through diet or supplements and a lower risk of all-cause mortality, including death from heart disease and cancer. However, more research is needed to confirm these findings and understand the underlying mechanisms. Check one study by pressing here
  • Improved Cellular Health: Increased autophagy and stress resistance induced by spermidine may contribute to healthy aging and potentially extend lifespan. Check one study by pressing here.

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5 g, 10 g, 30 g, 60 g, 100 g

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